產(chǎn)品名稱:APC-Cy?7 大鼠抗小鼠 CD45 抗體；APC-Cy?7 Rat Anti-Mouse CD45
中文名稱:APC-Cy?7 大鼠抗小鼠 CD45 抗體
英文名稱:APC-Cy?7 Rat Anti-Mouse CD45
APC-Cy?7 Rat Anti-Mouse CD45 產(chǎn)品介紹：
Material Number: 557659
Alternate Name: Leukocyte Common Antigen (LCA), Ly-5, T200
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: 30-F11
Immunogen: Mouse Thymus / Spleen
Isotype: Rat (LOU) IgG2b, κ
Reactivity: QC Testing: Mouse
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
APC-Cy?7 Rat Anti-Mouse CD45 Description：
The 30-F11 clone has been reported to react with all isoforms and both alloantigens of CD45, which is found on hematopoietic stem cells and
all cells of hematopoietic origin, except erythrocytes. CD45 is a transmembrane glycoprotein which is expressed at high levels on the
cell-surface, and its presence distinguishes leukocytes from non-hematopoietic cells. CD45 is a member of the Protein Tyrosine Phosphatase
(PTP) family, where the intracellular carboxy-terminal region contains two PTP catalytic domains, and the extracellular region is highly
variable due to alternative splicing of exons 4, 5, and 6 (designated as A, B, and C, respectively). CD45 isoforms play complex roles in T-cell
and B-cell antigen receptor signal transduction and the CD45 isoforms detected in the mouse are cell type-, maturation-, and activation
state-specific.
APC-Cy?7 Rat Anti-Mouse CD45 Preparation and Storage：
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with APC-Cy7 under optimum conditions, and unconjugated antibody and free APC-Cy7 were removed.
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
