PE Mouse Anti-Human CD274
產(chǎn)品名稱: PE Mouse Anti-Human CD274
產(chǎn)品型號(hào): BD-557924
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無(wú)相關(guān)文檔
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PE Mouse Anti-Human CD274
的詳細(xì)介紹
產(chǎn)品名稱:PE 小鼠抗人 CD274 抗體;PE Mouse Anti-Human CD274
中文名稱:PE 小鼠抗人 CD274 抗體
英文名稱:PE Mouse Anti-Human CD274
PE Mouse Anti-Human CD274 產(chǎn)品介紹:
Material Number: 557924
Alternate Name: B7-H1, PD-L1
Size: 100 tests
Vol. per Test: 20 μl
Clone: MIH1
Isotype: Mouse IgG1, κ
Reactivity: QC Testing: Human
Storage Buffer: Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
PE Mouse Anti-Human CD274 Description:
PD-L1 and PD-L2 are newly discovered members of the B7 family are the ligands for the program death 1 (PD-1) receptor. They are
expressed on immature dendritic cells and mature dendritic cells. PD-L1, also called B7-H1, is expressed on antigen-presenting cells,
including IFN-γ-stimulated monocytes, and activated human and murine dendritic cells. Monoclonal antibodies that block PD-L1 and PD-L2
on dendritic cells result in enhanced T cell proliferation and cytokine production. PD-L1 is also expressed on placental trophoblasts,
myocardial endothelium, cortical thymic epithelial cells, and on most carcinomas. Studies show overlapping functions of PD-L1 and PD-L2
and indicate an important role for the PD-L:PD-1 pathway in regulating T cell responses.
PE Mouse Anti-Human CD274 Preparation and Storage:
The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.
Store undiluted at 4° C and protected from prolonged exposure to light. Do not freeze.