647 Rat Anti-Human CD294
產(chǎn)品名稱: 647 Rat Anti-Human CD294
產(chǎn)品型號(hào): BD-558042
產(chǎn)品展商: BD Pharmingen
產(chǎn)品文檔: 無(wú)相關(guān)文檔
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647 Rat Anti-Human CD294
的詳細(xì)介紹
產(chǎn)品名稱:647 大鼠抗人 CD294 抗體;647 Rat Anti-Human CD294
中文名稱:647 大鼠抗人 CD294 抗體
英文名稱:647 Rat Anti-Human CD294
647 Rat Anti-Human CD294 產(chǎn)品介紹:
Material Number: 558042
Alternate Name: CRTH2; PTGDR2 ; Prostaglandin D2 receptor 2; DL1R; DP2; GPR44
Size: 0.1 mg
Concentration: 0.2 mg/ml
Clone: BM16
Immunogen: Human CRTH2 Transfected Cell Line
Isotype: Rat (WI) IgG2a, κ
Reactivity: QC Testing: Human
Workshop: VIII
Storage Buffer: Aqueous buffered solution containing ≤0.09% sodium azide.
647 Rat Anti-Human CD294 Description:
The BM16 monoclonal antibody specifically binds to CD294. CD294 is encoded by PTGDR2 (Prostaglandin D2 receptor 2) and is also
known as CRTH2 (chemoattractant receptor-homologous molecule expressed on Th2 cells), GPR44 (G protein-coupled receptor 44), DL1R,
and DP2. CD294 is a member of the G protein-coupled leukocyte chemoattractant receptor family and it is expressed on Th2, but not Th1 type
cells. CD294 is detectable on CD4+ T cells in fresh PBMC but not on B cells and NK cells. CD294 is also expressed on peripheral blood
basophils and eosinophils, suggesting its involvement allergic reactions. Phenotypic analysis of CD4+ T cells expressing CRTH2
demonstrated that they were also CD45RA-negative and CD45RO+ and CD25+. These cells produce Th2- but little or no Th1-type cytokines
upon stimulation with PMA and Ionomycin.
647 Rat Anti-Human CD294 Preparation and Storage:
Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.