人纖溶酶原激活劑抑制因子-1|Human PAI-1
產(chǎn)品名稱: 人纖溶酶原激活劑抑制因子-1|Human PAI-1
產(chǎn)品型號: C02-140-04-100ug
產(chǎn)品展商: peprotech
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
人纖溶酶原激活劑抑制因子-1|Human PAI-1系列產(chǎn)品主要適用于試驗室或生化科研相關(guān)試驗，CANSPEC品質(zhì)提供的人纖溶酶原激活劑抑制因子-1|Human PAI-1性能**，中文名稱為人纖溶酶原激活劑抑制因子-1|Human PAI-1。產(chǎn)品人纖溶酶原激活劑抑制因子-1|Human PAI-1以其優(yōu)良的品質(zhì)滿足您不同科研實驗的多種需求。
人纖溶酶原激活劑抑制因子-1|Human PAI-1
的詳細介紹
產(chǎn)品名稱：人纖溶酶原激活劑抑制因子-1|Human PAI-1
產(chǎn)品規(guī)格：
| C02-140-04-100ug | Human PAI-1 | 100ug | ￥18,200 |
| C02-140-04-10ug | 人纖溶酶原激活劑抑制因子-1|Human PAI-1 | 10ug | ￥1,960 |
| C02-140-04-1mg | 人纖溶酶原激活劑抑制因子-1|Human PAI-1 | 1mg | ￥72,800 |
| C02-140-04-2ug | 人纖溶酶原激活劑抑制因子-1|Human PAI-1 | 2ug | ￥680 |
| C02-140-04-500ug | 人纖溶酶原激活劑抑制因子-1|Human PAI-1 | 500ug | ￥43,680 |
單 位：瓶
關(guān) 鍵 字：人纖溶酶原激活劑抑制因子-1|Human PAI-1
CANSPEC品質(zhì)提供的人纖溶酶原激活劑抑制因子-1|Human PAI-1 性能**，英文名稱人纖溶酶原激活劑抑制因子-1|Human PAI-1，簡稱為人纖溶酶原激活劑抑制因子-1|Human PAI-1，中文名稱為人纖溶酶原激活劑抑制因子-1|Human PAI-1。
產(chǎn)品人纖溶酶原激活劑抑制因子-1|Human PAI-1以其優(yōu)良的品質(zhì)滿足您不同實驗的多種需求。并保證每批 人纖溶酶原激活劑抑制因子-1|Human PAI-1的質(zhì)量和人纖溶酶原激活劑抑制因子-1|Human PAI-1品質(zhì)優(yōu)良。
Synonyms : | Plasminogen Activator Inhibitor-1, Serpin E1 |
Description : | Plasminogen Activator Inhibitor-1 (PAI-1, Serpin E1) is a member of the serpin family of serine protease inhibitors, and is the primary inhibitor of urokinase and tissue plasminogen activator (tPA). PAI-1 is expressed predominantly in adipose, liver and vascular tissues, and is also produced by certain tumor cells. Elevated levels of PAI-1 are associated with obesity, diabetes and cardiovascular disease, and increased production of PAI-1 is induced by various obesity related factors such as TNFα, glucose, insulin, and very-low-density lipoprotein. The obesity related elevation of PAI-1 levels along with the consequential deficiency in plasminogen activators can lead directly to increased risk of thrombosis and other coronary diseases. Accordingly, PAI-1 has been implicated as an important molecular link between obesity and coronary disease. PAI-1 can also specifically bind vitronectin (VTN) to form a stable active complex with an increased circulatory half life relative to free PAI-1. Recombinant human PAI-1 is a 42.7 kDa protein containing 379 amino acid residues. |
Catalog #: | 140-04 |
Source : | E.coli |
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted PAI-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles. |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per μg (1EU/μg). |
Biological Activity : | Determined by its inhibitory effect against single chain tPA induced cleavage of a chromogenic substrate in Imidazole Buffer at 37oC. Half maximal inhibition against 1.0 μg/ml of single chain tPA was obtained at a concentration of 2.0 μg/ml. |
AA Sequence : | MVHHPPSYVA HLASDFGVRV FQQVAQASKD RNVVFSPYGV ASVLAMLQLT TGGETQQQIQ AAMGFKIDDK GMAPALRHLY KELMGPWNKD EISTTDAIFV QRDLKLVQGF MPHFFRLFRS TVKQVDFSEV ERARFIINDW VKTHTKGMIS NLLGKGAVDQ LTRLVLVNAL YFNGQWKTPF PDSSTHRRLF HKSDGSTVSV PMMAQTNKFN YTEFTTPDGH YYDILELPYH GDTLSMFIAA PYEKEVPLSA LTNILSAQLI SHWKGNMTRL PRLLVLPKFS LETEVDLRKP LENLGMTDMF RQFQADFTSL SDQEPLHVAQ ALQKVKIEVN ESGTVASSST AVIVSARMAP EEIIMDRPFL FVVRHNPTGT VLFMGQVMEP |
PubMed Link : | PAI-1 |
Country of Origin : | USA |
