人白細(xì)胞介素-2受體|Human sIL-2 Receptor
產(chǎn)品名稱: 人白細(xì)胞介素-2受體|Human sIL-2 Receptor
產(chǎn)品型號: C02-200-02R-100ug
產(chǎn)品展商: peprotech
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
人白細(xì)胞介素-2受體|Human sIL-2 Receptor系列產(chǎn)品主要適用于試驗(yàn)室或生化科研相關(guān)試驗(yàn)，CANSPEC品質(zhì)提供的人白細(xì)胞介素-2受體|Human sIL-2 Receptor性能**，中文名稱為人白細(xì)胞介素-2受體|Human sIL-2 Receptor。產(chǎn)品人白細(xì)胞介素-2受體|Human sIL-2 Receptor以其優(yōu)良的品質(zhì)滿足您不同科研實(shí)驗(yàn)的多種需求。
人白細(xì)胞介素-2受體|Human sIL-2 Receptor
的詳細(xì)介紹
產(chǎn)品名稱：人白細(xì)胞介素-2受體|Human sIL-2 Receptor
產(chǎn)品規(guī)格：
| C02-200-02R-100ug | 人白細(xì)胞介素-2受體|Human sIL-2 Receptor | 100ug | ￥9,800 |
| C02-200-02R-1mg | 人白細(xì)胞介素-2受體|Human sIL-2 Receptor | 1mg | ￥39,200 |
| C02-200-02R-25ug | 人白細(xì)胞介素-2受體|Human sIL-2 Receptor | 25ug | ￥1,960 |
| C02-200-02R-500ug | 人白細(xì)胞介素-2受體|Human sIL-2 Receptor | 500ug | ￥23,520 |
| C02-200-02R-5ug | 人白細(xì)胞介素-2受體|Human sIL-2 Receptor | 5ug | ￥680 |
單 位：瓶
關(guān) 鍵 字：人白細(xì)胞介素-2受體|Human sIL-2 Receptor
CANSPEC品質(zhì)提供的 人白細(xì)胞介素-2受體|Human sIL-2 Receptor性能**，英文名稱人白細(xì)胞介素-2受體|Human sIL-2 Receptor,簡稱為人白細(xì)胞介素-2受體|Human sIL-2 Receptor，中文名稱為人白細(xì)胞介素-2受體|Human sIL-2 Receptor。
產(chǎn)品人白細(xì)胞介素-2受體|Human sIL-2 Receptor以其優(yōu)良的品質(zhì)滿足您不同實(shí)驗(yàn)的多種需求。并保證每批 人白細(xì)胞介素-2受體|Human sIL-2 Receptor的質(zhì)量和人白細(xì)胞介素-2受體|Human sIL-2 Receptor品質(zhì)優(yōu)良。
Synonyms : | soluble IL-2 receptor, TAC-antigen, CD25 antigen |
Description : | The IL-2 receptor system consists of three non-covalently linked subunits termed IL-2Rα, IL-2Rβ, and IL-2Rγ. The IL-2Rα is a type I transmembrane protein consisting of a 219 amino acid extracellular domain, a 19 amino acid transmembrane domain and a 13 amino acid intracellular domain, which is not involved in the transduction of IL-2 signals. Proteolytic processing of IL-2Rα releases the entire extracellular domain of IL-2Rα thereby generating a 219 amino acid soluble protein called soluble IL-2Rα (sIL-2Rα). The homodimeric form binds IL-2 (KD=10nM) and facilitates IL-2 signaling. The secreted sIL-2Rα is expressed on leukemia cells, lymphoma cells, newly activated T and B cells, as well as on approximately 10% of NK cells. Recombinant human sIL-2Rα is a 24.8 kDa protein containing 219 amino acid residues consisting of only the extracellular domain of IL-2Rα. Due to glycosylation, IL-2Rα has an approximate molecular weight of 31 kDa based on SDS-PAGE gel and Mass Spectrometry.* Manufactured using (BTI-Tn-5B1-4) cells under license from the Boyce Thompson Institute for Plant Research, Inc. |
Catalog #: | 200-02R |
Source : | (BTI-Tn-5B1-4) High-5 Insect Cells* |
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted sIL-2Rα is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles. |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per µg (1EU/µg). |
Biological Activity : | Determined by its ability to increase the proliferation effect of IL-2 in murine CTLL-2 cells. In the presence of 1 ng/ml of recombinant IL-2, the expected ED50 for this effect is between 0.5 - 1.5 µg/ml. |
AA Sequence : | ELCDDDPPEI PHATFKAMAY KEGTMLNCEC KRGFRRIKSG SLYMLCTGNS SHSSWDNQCQ CTSSATRNTT KQVTPQPEEQ KERKTTEMQS PMQPVDQASL PGHCREPPPW ENEATERIYH FVVGQMVYYQ CVQGYRALHR GPAESVCKMT HGKTRWTQPQ LICTGEMETS QFPGEEKPQA SPEGRPESET SCLVTTTDFQ IQTEMAATME TSIFTTEYQ |
PubMed Link : | IL-2+AND+receptor+AND+alpha |
Country of Origin : | USA |
