人白細胞介素-6受體|Human IL-6 Receptor
產(chǎn)品名稱: 人白細胞介素-6受體|Human IL-6 Receptor
產(chǎn)品型號: C02-200-06R-100ug
產(chǎn)品展商: peprotech
產(chǎn)品文檔: 無相關(guān)文檔
簡單介紹
人白細胞介素-6受體|Human IL-6 Receptor系列產(chǎn)品主要適用于試驗室或生化科研相關(guān)試驗，CANSPEC品質(zhì)提供的人白細胞介素-6受體|Human IL-6 Receptor性能**，中文名稱為人白細胞介素-6受體|Human IL-6 Receptor。產(chǎn)品人白細胞介素-6受體|Human IL-6 Receptor以其優(yōu)良的品質(zhì)滿足您不同科研實驗的多種需求。
人白細胞介素-6受體|Human IL-6 Receptor
的詳細介紹
產(chǎn)品名稱：人白細胞介素-6受體|Human IL-6 Receptor
產(chǎn)品規(guī)格：
| C02-200-06R-100ug | 人白細胞介素-6受體|Human IL-6 Receptor | 100ug | ￥11,200 |
| C02-200-06R-1mg | 人白細胞介素-6受體|Human IL-6 Receptor | 1mg | ￥50,400 |
| C02-200-06R-20ug | 人白細胞介素-6受體|Human IL-6 Receptor | 20ug | ￥1,960 |
| C02-200-06R-500ug | 人白細胞介素-6受體|Human IL-6 Receptor | 500ug | ￥30,240 |
| C02-200-06R-5ug | 人白細胞介素-6受體|Human IL-6 Receptor | 5ug | ￥680 |
單 位：瓶
關(guān) 鍵 字：人白細胞介素-6受體|Human IL-6 Receptor
CANSPEC品質(zhì)提供的人白細胞介素-6受體|Human IL-6 Receptor性能**，英文名稱人白細胞介素-6受體|Human IL-6 Receptor，簡稱為人白細胞介素-6受體|Human IL-6 Receptor，中文名稱為人白細胞介素-6受體|Human IL-6 Receptor。
產(chǎn)品 人白細胞介素-6受體|Human IL-6 Receptor以其優(yōu)良的品質(zhì)滿足您不同實驗的多種需求。并保證每批人白細胞介素-6受體|Human IL-6 Receptor的質(zhì)量和人白細胞介素-6受體|Human IL-6 Receptor品質(zhì)優(yōu)良。
Synonyms : | soluble IL-6 receptor alpha, B cell stimulatory factor-2, CD126 |
Description : | IL-6 mediates its biological effects through the type I IL-6 receptor system that consists of two chains, IL-6R α and gp130. The IL-6R α chain is the binding component specific to IL-6; while the gp130 only transmits signals of IL-6 when bound to IL-6R α. The gp130 also can transmit signals from LIF, OSM, CNTF, IL-11 and CT-1 in conjunction with other receptor subunits. The low-affinity binding site for IL-6 is composed of IL-6R α alone. IL-6R α is expressed in a wide range of cells including T cells, fibroblasts and macrophages. Soluble IL-6R α which consists of only the extracellular domain of the IL-6R α chain, acts as an agonist of IL-6 activity at low concentrations. Recombinant human sIL-6R α is a 37.6 kDa protein consisting of the extracellular domain of the IL-6R α chain (338 amino acid residues). |
Catalog #: | 200-06R |
Source : | HEK 293 cells |
Stability : | The lyophilized protein is stable for at least 2 years from date of receipt at -200C. Reconstituted sIL-6R α is stable for at least 3 months when stored in working aliquots with a carrier protein at -200C. Avoid repeated freeze/thaw cycles. |
Purity : | Greater than 98% by SDS-PAGE gel and HPLC analyses. |
Endotoxin Level : | Endotoxin level is less than 0.1 ng per µg (1EU/µg). |
Biological Activity : | The ED50 was determined by it's ability to intensify the IL-6 induced growth inhibition of murine M1 cells is ≤ 5.0 ng/ml, in the presence of 20 ng/ml of rhIL-6. |
Selected References : | Selected List of References Citing This PeproTech Product |
AA Sequence : | LAPRRCPAQE VARGVLTSLP GDSVTLTCPG VEPEDNATVH WVLRKPAAGS HPSRWAGMGR RLLLRSVQLH ASGNYSCYRA GRPAGTVHLL VDVPPEEPQL SCFRKSPLSN VVCEWGPRST PSLTTKAVLL VRKFQNSPAE DFQEPCQYSQ ESQKFSCQLA VPEGDSSFYI VSMCVASSVG SKFSKTQTFQ GCGILQPAPP ANITVTAVAR NPRWLSVTWQ DPHSWNSSFY RLRFELRYRA ERSKTFTTWM VKDLQHHCVI HDAWSGLRHV VQLRAQEEFG QGEWSEWSPE AMGTPWTESR SPPAENEVST PMQALTTNKD DDNILFRDSA NATSLPVQD |
PubMed Link : | IL-6+AND+receptor-alpha |
Country of Origin : | USA |
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