Synonyms :

Growth Regulated Protein/Melanoma Growth Stimulatory Activity, GRO alpha, MGSA alpha, CXCL1, NAP-3, GRO1, KC (murine) CINC (rat)

Description :

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. GRO/MGSA also stimulates mitogenesis in certain human melanoma cells. Recombinant human GRO/MGSA is a 7.8 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Catalog #:

300-11

Source :

E.coli

Stability :

The lyophilized protein is stable for at least 2 years from date of receipt at -20⁰C. Reconstituted GRO/MGSA is stable for at least 3 months when stored in working aliquots with a carrier protein at -20⁰C. Avoid repeated freeze/thaw cycles.

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-50.0 ng/ml.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN

PubMed Link :

GRO-alpha+AND+human

Country of Origin :

USA