Synonyms :

Growth Regulated Protein/Melanoma Growth Stimulatory Activity (MGSA beta), CXCL2, MIP-2, GRO2

Description :

All three isoforms of GRO are CXC chemokines that can signal through the CXCR1 or CXCR2 receptors. The GRO proteins chemoattract and activate neutrophils and basophils. Recombinant human GRO-beta is a 7.9 kDa protein consisting of 73 amino acids including the 'ELR' motif common to the CXC chemokine family that bind to CXCR1 or CXCR2.

Catalog #:

300-39

Source :

E.coli

Stability :

The lyophilized protein is stable for at least 2 years from date of receipt at -20⁰C. Reconstituted GRO-beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20⁰C. Avoid repeated freeze/thaw cycles.

Purity :

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin Level :

Endotoxin level is less than 0.1 ng per µg (1EU/µg).

Biological Activity :

Determined by its ability to chemoattract CXCR2 transfected 293 cells using a concentration range of 10.0-100.0 ng/ml.

Selected References :

Selected List of References Citing This PeproTech Product

AA Sequence :

APLATELRCQ CLQTLQGIHL KNIQSVKVKS PGPHCAQTEV IATLKNGQKA CLNPASPMVK KIIEKMLKNG KSN

PubMed Link :

GRO-beta+AND+human

Country of Origin :

USA